Recurrent acute pancreatitis is not uncommon in our clinical setting

Autores/as

DOI:

https://doi.org/10.47892/rgp.2023.431.1412

Palabras clave:

Pancreatitis, Recurrence, Cholecystectomy

Resumen

Data on recurrent episodes of acute pancreatitis (RAP) are scarce. The aim of the study was to evaluate our rate of RAP and risks factors. This is a retrospective, single-center, study of consecutive patients admitted for AP and followed-up. Patients with more than one AP attack (RAP) were compared with patients with only a single AP episode (SAP) Clinical, demographic, outcome measures and severity were studied. 561 patients were included and follow-up over a mean 67.63 months’ time. Our rate of RAP was 18,9%. Most patients suffered form only one episode of RAP (93%). Etiology of RAP episodes was mainly biliary (67%). On univariate analysis younger age (p 0.004), absence of high blood pressure (p 0.013) and absent of SIRS (p 0.022) were associated with recurrence of AP. On multivariate analysis only younger age was related to RAP (OR 1.015 95%IC 1.00-1.029). There were no statistical differences in outcome measures between both cohorts. RAP had a milder course in terms of severity (SAP 19% moderately severe/severe versus 9% in SAP). Almost 70% of the biliary RAP patients did not have a cholecystectomy performed. In this subset of patients, age OR 0.964 (95%IC 0.946-0.983), cholecystectomy OR 0.075 (95%IC 0.189-0.030) and cholecystectomy plus ERCP OR 0.190 (95%IC 0.219-0.055) were associated with absent of RAP. The rate of RAP in our series was 18,9%. Younger age was the only risk factor associated. Biliary etio ogy accounts for a large proportion of our RAP which could have been prevented with cholecystectomy or cholecystectomy plus ERCP.

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Biografía del autor/a

María Lourdes Ruiz-Rebollo, Servicio de Aparato Digestivo, Hospital Clínico Universitario, Valladolid, España

LICENCIADO ESPECIALISTA

SERVICIO DE APARATO DIGESTIVO

HOSPITAL CLÍNICO UNIVERSITARIO

47003 VALLADOLID

ESPAÑA

María Fe Muñoz-Moreno, Unidad de Apoyo a la Investigación, Hospital Clínico Universitario, Valladolid, España

médico adjunto

SERVICIO DE APARATO DIGESTIVO
HOSPITAL CLÍNICO UNIVERSITARIO
VALLADOLID
SPAIN

Reyes Busta-Nistal, Servicio de Aparato Digestivo, Hospital Clínico Universitario, Valladolid, España

Licenicada en Ciencias Exactas

UNIDAD DE APOYO A LA INVESTIGACIÓN
HOSPITAL CLÍNICO UNIVERSITARIO
VALLADOLID
SPAIN

María Antonella Rizzo- Rodríguez, Servicio de Aparato Digestivo, Hospital Clínico Universitario, Valladolid, España

MÉDICO RESIDENTE

SERVICIO DE APARATO DIGESTIVO
HOSPITAL CLÍNICO UNIVERSITARIO
VALLADOLID
SPAIN

Sandra Izquierdo-Santervás, Servicio de Aparato Digestivo, Hospital Clínico Universitario, Valladolid, España

MÉDICO RESIDENTE

SERVICIO DE APARATO DIGESTIVO
HOSPITAL CLÍNICO UNIVERSITARIO
VALLADOLID
SPAIN

Citas

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Publicado

11.04.2023

Cómo citar

1.
Ruiz-Rebollo ML, Muñoz-Moreno MF, Busta-Nistal R, Rizzo- Rodríguez MA, Izquierdo-Santervás S. Recurrent acute pancreatitis is not uncommon in our clinical setting. Rev Gastroenterol Peru [nternet]. 11 de abril de 2023 [citado 15 de junio de 2024];43(1):31-7. isponible en: https://revistagastroperu.com/index.php/rgp/article/view/1412

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ARTÍCULOS ORIGINALES