Gastric cancer screening in Chile. Results of the National Health Survey 2016-2017

Authors

DOI:

https://doi.org/10.47892/rgp.2025.451.1870

Keywords:

Stomach Neoplasms, Early Detection of Cancer, Mass screening, Chile, Health care surveys

Abstract

Introduction: Gastric cancer (GC) is the leading cause of oncologic death in Chile. Since 2006, the health authority has recommended upper gastrointestinal endoscopy (UGE) for symptomatic individuals ≥40 years old. In 2010, the UGE coverage in this group was estimated at 14%. Objective: To evaluate UGE coverage for GC screening in Chile using data from the National Health Survey (NHS) 2016-17. Materials and methods: The NHS 2016-17 surveyed 6,233 adults about the presence of persistent epigastric pain, possible upper gastrointestinal bleeding, and UGE. UGE prevalences among different groups were compared, and multivariate models adjusted for sex, age, income, education, area of residence, and belonging to an indigenous group were constructed. Results: Both persistent epigastric pain and possible upper gastrointestinal bleeding were reported by 4.7%, being higher in the ≥ 40-year-old group and lower educational level. The prevalence of UGE performed at least once in life reached 20.8%, being higher in women, ≥40 years old, privately insured individuals, and the non-indigenous Hispanic population. The coverage of UGE in the last year among symptomatic individuals ≥40 years old increased to 19.8%, with no significant differences in the multivariate analysis. Conclusion: The coverage of UGE in the last year in symptomatic individuals ≥40 years old for GC screening in Chile is 19.8%. Lowest socioeconomic status and indigenous peoples are disadvantaged groups.

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References

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209-249. doi: 10.3322/caac.21660.

Ministerio de Salud, Departamento de Epidemiología. Informe de Vigilancia de Cáncer. Análisis de Mortalidad. Década 2009-2018 [Internet]. Santiago de Chile; 2020 [citado el 26 de octubre de 2022]. Disponible en: http://epi.minsal.cl/ wp-content/uploads/2021/05/Informe_Mortalidad_por_Cancer_2009_2018.pdf

Caglevic C, Silva S, Mahave M, Rolfo C, Gallardo J. The current situation for gastric cancer in Chile. Ecancermedicalscience. 2016;10:707. doi: 10.3332/ecancer.2016.707.

Ministerio de Salud, Departamento de Epidemiología. Informe de Vigilancia de Cáncer. Análisis de Mortalidad Prematura y AVPP por Cáncer. Década 2009-2018 [Internet]. Santiago de Chile; 2021 [citado el 26 de octubre de 2022]. Disponible en: https://www.minsal.cl/wp-content/ uploads/2022/01/Informe-Mortalidad-Prematura-y-AVPPpor-C%C3%A1ncer-2009-2018.pdf

Huang RJ, Laszkowska M, In H, Hwang JH, Epplein M. Controlling Gastric Cancer in a World of Heterogeneous Risk. Gastroenterology. 2023;164(5):736-751. doi: 10.1053/j.gastro.2023.01.018.

Malfertheiner P, Megraud F, Rokkas T, Gisbert JP, Liou JM, Schulz C, et al. Management of infection: the Maastricht VI/ Florence consensus report. Gut. 2022:gutjnl-2022-327745. doi: 10.1136/gutjnl-2022-327745.

Yang L, Kartsonaki C, Yao P, de Martel C, Plummer M, Chapman D, et al. The relative and attributable risks of cardia and non-cardia gastric cancer associated with Helicobacter pylori infection in China: a case-cohort study. Lancet Public Health. 2021;6(12):e888-e896. doi: 10.1016/S2468-2667(21)00164-X.

Choi KS, Jun JK, Suh M, Park B, Noh DK, Song SH, et al. Effect of endoscopy screening on stage at gastric cancer diagnosis:results of the National Cancer Screening Programme in Korea. Br J Cancer. 2015;112(3):608-12. doi: 10.1038/bjc.2014.608.

Kakushima N, Fujishiro M, Chan SM, Cortas GA, Dinis-Ribeiro M, Gonzalez R, et al. Proposal of minimum elements for screening and diagnosis of gastric cancer by an international Delphi consensus. DEN Open. 2022;2(1):e97. doi: 10.1002/ deo2.97.

Yue H, Shan L, Bin L. The significance of OLGA and OLGIM staging systems in the risk assessment of gastric cancer: a systematic review and meta-analysis. Gastric Cancer. 2018;21(4):579- 587. doi: 10.1007/s10120-018-0812-3.

Shah SC, Piazuelo MB, Kuipers EJ, Li D. AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review. Gastroenterology. 2021;161(4):1325-1332. e7. doi: 10.1053/j.gastro.2021.06.078.

Gawron AJ, Shah SC, Altayar O, Davitkov P, Morgan D, Turner K, et al. AGA Technical Review on Gastric Intestinal Metaplasia-Natural History and Clinical Outcomes. Gastroenterology. 2020;158(3):705-731.e5. doi: 10.1053/j.gastro.2019.12.001.

Ajani JA, Lee J, Sano T, Janjigian YY, Fan D, Song S. Gastric adenocarcinoma. Nat Rev Dis Primers. 2017;3:17036. doi: 10.1038/nrdp.2017.36.

Ministerio de Salud, Departamento Manejo Integral del Cáncer y otros Tumores. Guía Clínica AUGE Cáncer Gástrico [Internet]. Santiago de Chile; 2021 [citado el 02 de diciembre de 2021] Disponible en: https://www.minsal.cl/sites/default/files/ files/GPC%20G%C3%A1strico%20(PL).pdf

Latorre SG, Álvarez OJ, Ivanovic-Zuvic SD, Valdivia CG, Margozzini MP, Chianale BJ, et al. Cobertura de la estrategia preventiva de cáncer gástrico en Chile: resultados de la Encuesta Nacional de Salud 2009-2010. Rev Med Chil. 2015;143(9):1198- 205. doi: 10.4067/S0034-98872015000900014.

von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. Declaración de la Iniciativa STROBE (Strengthening the Reporting of Observational studies in Epidemiology): directrices para la comunicación de estudios observacionales. Gac Sanit. 2008;82(3):144–50. doi: 10.1157/13119325.

West BT, Berglund P, Heeringa SG. A closer examination of subpopulation analysis of complex-sample survey data. Stata J. 2008;8:520-31. doi 10.1177/1536867X0800800404.

Chang Y, Cho B, Son KY, Shin DW, Shin H, Yang HK, et al. Determinants of gastric cancer screening attendance in Korea: a multi-level analysis. BMC Cancer 2015;15:336. doi: 10.1186/ s12885-015-1328-4.

Mülder DT, Hahn AI, Huang RJ, Zhou MJ, Blake B, Omofuma O, et al. Prevalence of Gastric Precursor Lesions in Countries With Differential Gastric Cancer Burden: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2024;22(8):1605- 1617.e46. doi: 10.1016/j.cgh.2024.02.023.

Ward ZJ, Walbaum M, Walbaum B, Guzman MJ, Jimenez de la Jara J, Nervi B, et al. Estimating the impact of the COVID-19 pandemic on diagnosis and survival of five cancers in Chile from 2020 to 2030: a simulation-based analysis. Lancet Oncol. 2021;22(10):1427-1437. doi: 10.1016/S1470-2045(21)00426-5.

Rollán A, Cortés P, Calvo A, Araya R, Bufadel ME, González R, et al. Diagnóstico precoz de cáncer gástrico. Propuesta de detección y seguimiento de lesiones premalignas gástricas: protocolo ACHED. Rev Med Chil. 2014;142(9):1181-92. doi: 10.4067/S0034-98872014000900013.

Corsi Ó, Pizarro M, Rollán A, Silva V, Araya R, Bufadel ME, et al. Estrategias para la prevención primaria y secundaria del cáncer gástrico: consenso chileno de panel de expertos con técnica Delfi. Gastroenterol Hepatol. 2024;47(8):845-857. doi: 10.1016/j.gastrohep.2024.01.008.

Published

03/31/2025

How to Cite

1.
Corsi Sotelo O, Fuentes-López E, Latorre Selvat G, Espinoza Sepúlveda MA, Margozzini Maira P, Monrroy Bravo H, Espino Espino A, Riquelme Pérez A. Gastric cancer screening in Chile. Results of the National Health Survey 2016-2017. Rev Gastroenterol Peru [nternet]. 2025 Mar. 31 [cited 2025 Dec. 16];45(1):24-31. vailable from: https://revistagastroperu.com/index.php/rgp/article/view/1870

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ARTÍCULOS ORIGINALES

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