Irritable bowel syndrome in medical students from Lima, Peru, during the COVID-19 pandemic, using virtual questionnaires according to the Rome IV criteria: prevalence and associated factors

Autores/as

DOI:

https://doi.org/10.47892/rgp.2024.442.1668

Palabras clave:

Irritable bowel syndrome, Students, medical, COVID-19, Diarrhea

Resumen

Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder, characterized by
changes of the intestinal habit associated with abdominal pain. This study analyzed factors
associated with this pathology during the COVID-19 pandemic, and it was seen that the impact of IBS was higher in young women who had ongoing studies in the medical field. Objectives: Determine the prevalence of IBS in medical students and explore the associated factors with the increase of its symptoms, through the use of digital tools. Materials and methods: Descriptive observational study with exploration of associations, with nonprobabilistic sampling, until reaching the minimum sample of 110 participants with a confidence interval of 95%, finally having a total sample of 131 students, distributed in 3 proportional and representative subgroups of the last 3 years of study of the medical career from a university from Lima, Peru. The inclusion criteria were students of both sexes and legal age, who gave their consent to participate and did not have risk factors for GI disease. Once the study was approved, the link of a validated virtual questionnaire was shared through the institutional email. To explore the associated factors, the Chi-square test was used with a statistical significance of p < 0.05. Results: Responses were obtained
from 195 students; 64 (32.82%) of them had at least one exclusion criteria, finally having a sample size of 131; 64 (48.85%) were women, and 52 (39.69%) were from 7th year. Using the Rome IV criteria, 23 participants were classified as having IBS, which indicates a prevalence of 17.56%, 14 (60.87%) of them were women and 10 (43.48%) were from the 7th year (last year of study of the medical career in Peru). It was observed that 1 in 3 students (32.06%) had chronic abdominal pain, and 1 in 2 (53.44%) reported having a history of Major Depression or Generalized Anxiety Disorder. Of the total, 51 (38.93%) had a history of having a positive COVID-19 test result. Regarding the associated factors, a significant association was only found between IBS and the diarrhea type, classified according to the Bristol Scale. Conclusions: The prevalence of IBS in medical students was 17.56%, the highest compared with studies in the general population and in medical students using Rome IV criteria. Of the associated factors, the clinical presentation of diarrhea, according to the Bristol scale, was associated with IBS.

Descargas

Los datos de descargas todavía no están disponibles.

Métricas

Cargando métricas ...

Citas

Golla R, Vuyyuru S, Kante B, Kumar P, Mathew DT, Makharia G, et al. Long-term gastrointestinal sequelae following COVID-19: A prospective follow-up cohort study. Clin Gastroenterol Hepatol. 2022;21(3):789-796.e1. doi: 10.1016/j.cgh.2022.10.015.

Marynowski M, Likońska A, Zatorski H, Fichna J. Role of environmental pollution in irritable bowel syndrome. World J Gastroenterol. 2015;21(40):11371-8. doi: 10.3748/wjg.v21.i40.11371.

Ford AC, Lacy BE, Talley NJ. Irritable bowel syndrome. N Engl J Med. 2017;376(26):2566-78. doi: 10.1056/NEJMra160754.

Aziz I, Törnblom H, Palsson OS, Whitehead WE, Simrén M. How the change in IBS criteria from Rome III to Rome IV impacts on clinical characteristics and key pathophysiological factors. Am J Gastroenterol. 2018;113(7):1017-25. doi: 10.1038/s41395-018-0074-z.

Drossman DA. Functional gastrointestinal disorders: History, pathophysiology, clinical features and Rome IV. Gastroenterology. 2016;150(6):1262-1279.e2. doi: 10.1053/j.gastro.2016.02.032.

Mearin F, Ciriza C, Mínguez M, Rey E, Mascort JJ, Peña E, et al. Guía de práctica clínica: síndrome del intestino irritable con estreñimiento y estreñimiento funcional en adultos: concepto, diagnóstico y continuidad asistencial. Semergen. 2017;43(1):43-56. doi: 10.1016/j.semerg.2016.06.009.

Lacy BE, Mearin F, Chang L, Chey WD, Lembo AJ, Simren M, et al. Bowel disorders. Gastroenterology. 2016;150(6):1393-1407.e5. doi: 10.1053/j.gastro.2016.02.031.

Gubatan J, Zikos T, Spear Bishop E, Wu J, Gottfried A, Becker L, et al. Gastrointestinal symptoms and healthcare utilization have increased among patients with functional gastrointestinal and motility disorders during the COVID-19 pandemic. Neurogastroenterol Motil. 2022;34(4):e14243. doi: 10.1111/nmo.14243.

Sperber AD, Bangdiwala SI, Drossman DA, Ghoshal UC, Simren M, Tack J, et al. Worldwide prevalence and burden of functional gastrointestinal disorders, results of Rome foundation global study. Gastroenterology. 2021;160(1):99-114.e3. doi: 10.1053/j.gastro.2020.04.014.

Alvizuri Gómez CM, Bellido Caparó Á, Samalvides Cuba F, Pinto Valdivia JL. Epidemiology and associated factors of irritable bowel syndrome in an Andean community from Peru. Rev Gastroenterol Peru. 2021;41(1):6-10. doi: 10.47892/rgp.2021.411.1236.

Pontet Y, Olano C. Prevalencia de síndrome de intestino irritable en América Latina. Rev Gastroenterol Peru. 2021;41(3):144-149. doi: 10.47892/rgp.2021.413.1154.

Oka P, Parr H, Barberio B, Black CJ, Savarino EV, Ford AC. Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol. 2020;5(10):908-17. doi: 10.1016/S2468-1253(20)30217-X.

Choghakhori R, Abbasnezhad A, Amani R, Alipour M. Sex-related differences in clinical symptoms, quality of life, and biochemical factors in irritable bowel syndrome. Dig Dis Sci. 2017;62(6):1550-60. doi: 10.1007/s10620-017-4554-6.

Akhondi N, Memar Montazerin S, Soltani S, Saneei P, Hassanzadeh Keshteli A, Esmaillzadeh A, et al. General and abdominal obesity in relation to the prevalence of irritable bowel syndrome. Neurogastroenterol Motil. 2019;31(4):e13549. doi: 10.1111/nmo.13549.

Lee C, Doo E, Choi JM, Jang S-H, Ryu H-S, Lee JY, et al. The increased level of depression and anxiety in irritable bowel syndrome patients compared with healthy controls: Systematic review and meta-analysis. J Neurogastroenterol Motil. 2017;23(3):349-62. doi: 10.5056/jnm16220.

Ghoshal UC, Ghoshal U, Rahman MM, Mathur A, Rai S, Akhter M, et al. Post-infection functional gastrointestinal disorders following coronavirus disease-19: A case-control study.

J Gastroenterol Hepatol. 2022;37(3):489-98. doi: 10.1111/jgh.15717.

Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus. J Virol. 2020;94(7):e00127-20. doi: 10.1128/JVI.00127-20.

Groff A, Kavanaugh M, Ramgobin D, McClafferty B, Aggarwal CS, Golamari R, et al. Gastrointestinal Manifestations of COVID-19: A Review of What We Know. Ochsner J. 2021;21(2):177-180. doi: 10.31486/toj.20.0086.

Tian Y, Rong L, Nian W, He Y. Review article: gastrointestinal features in COVID-19 and the possibility of faecal transmission. Aliment Pharmacol Ther. 2020;51(9):843-51. doi: 10.1111/apt.15731.

Vargas-Matos I, Ng-Sueng LF, Flores-Arriaga J, Beltrán-Flores S, Lema-Correa M, Piscoya A, et al. Superposición del síndrome de intestino irritable y dispepsia funcional basados en criterios ROMA III en estudiantes de medicina de una universidad privada de Lima, Perú. Rev Gastroenterol Peru. 2015;35(3):219-25.

Black CJ, Craig O, Gracie DJ, Ford AC. Comparison of the Rome IV criteria with the Rome III criteria for the diagnosis of irritable bowel syndrome in secondary care. Gut. 2021;70(6):1110-6. doi: 10.1136/gutjnl-2020-322519.

Rodríguez Yunta E. Comités de evaluación ética y científica para la investigación en seres humanos y las pautas CIOMS 2002. Acta Bioeth. 2004;10(1):37-48. doi: 10.4067/S1726-569X2004000100005.

Council for International Organizations of Medical Sciences. Pauta 22: Uso de datos obtenidos en entornos en línea y de herramientas digitales en la investigación relacionada con la salud. In: Pautas éticas internacionales para la investigación relacionada con la salud con seres humanos. 4ta ed. Ginebra: CIOMS; 2017. p. 93-5.

Yoon K, Kim N. Roles of sex hormones and gender in the gut Microbiota. J Neurogastroenterol Motil. 2021;27(3):314-25. doi: 10.5056/jnm20208.

Björkman I, Jakobsson Ung E, Ringström G, Törnblom H, Simrén M. More similarities than differences between men and women with irritable bowel syndrome. Neurogastroenterol Motil. 2015;27(6):796-804. doi: 10.1111/nmo.12551.

Organización Mundial de la Salud. La pandemia de COVID-19 aumenta en un 25% la prevalencia de la ansiedad y la depresión en todo el mundo. Ginebra: OMS; 2022 [citado el 24 de Octubre de 2023]. Disponible en: https://www.who.int/es/news/item/02-03-2022-covid-19-pandemic-triggers-25-increase-in-prevalence-of-anxiety-and-depression-worldwide

Mariños-Llajaruna HR, Chafloque-Chafloque A. Asociación entre el Síndrome de Intestino Irritable y la ansiedad y depresión en pacientes atendidos en el Hospital Regional Docente de Trujillo. Rev médica Trujillo. 2019;14(4):181-8. doi: 10.17268/rmt.2019.v14i04.05.

Gutiérrez-Rojas L, Porras-Segovia A, Dunne H, Andrade-González N, Cervilla JA. Prevalence and correlates of major depressive disorder: a systematic review. Brazilian Journal of Psychiatry. 2020;42(6):657-672. doi: 10.1590/1516-4446-2020-0650.

Vargas M, Talledo-Ulfe L, Heredia P, Quispe-Colquepisco S, Mejia CR. Influencia de los hábitos en la depresión del estudiante de medicina peruano: estudio en siete departamentos. Rev Colomb Psiquiatr. 2018;47(1):32-6. doi: 10.1016/j.rcp.2017.01.008.

Szuhany KL, Simon NM. Anxiety disorders: A review. JAMA. 2022;328(24):2431-45. doi: 10.1001/jama.2022.22744.

Sekhon S, Gupta V. Mood Disorder. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023.

Mejía-Zambrano H, Ramos-Calsín L. Prevalencia de los principales trastornos mentales durante la pandemia por COVID-19. Rev Neuropsiquiatr. 2022;85(1):72-82. doi: 10.20453/rnp.v85i1.4157.

Pacheco-Vasquez DR, Guerrero-Alcedo JM. Prevalencia de trastornos mentales en población peruana con COVID-19 atendida en el programa “Te Cuido Perú”. Archivos Venezolanos de Farmacología y Terapéutica. 2021;40(9):902-6.

Mohammadian Khonsari N, Shafiee G, Zandifar A, Mohammad Poornami S, Ejtahed H-S, Asayesh H, et al. Comparison of psychological symptoms between infected and non-infected COVID-19 health care workers. BMC Psychiatry. 2021;21(1):170. doi: 10.1186/s12888-021-03173-7.

Henick D, Italiano T, Person H, Keefer L. Medical students’ knowledge and perception of irritable bowel syndrome in comparison to inflammatory bowel disease. Neurogastroenterol Motil. 2023;35(10):e14576. doi: 10.1111/nmo.14576.

Descargas

Publicado

26.06.2024

Cómo citar

1.
Medina-Pérez R, Chavarria-Ocmin R, Espinoza-Ríos J, Samalvides-Cuba F. Irritable bowel syndrome in medical students from Lima, Peru, during the COVID-19 pandemic, using virtual questionnaires according to the Rome IV criteria: prevalence and associated factors. Rev Gastroenterol Peru [nternet]. 26 de junio de 2024 [citado 24 de julio de 2024];44(2). isponible en: https://revistagastroperu.com/index.php/rgp/article/view/1668

Número

Sección

ARTÍCULOS ORIGINALES

Artículos más leídos del mismo autor/a

1 2 > >>