Surgical or endoscopic management for post-ERCP large transmural duodenal perforations: a randomized prospective trial

Autores/as

  • Everson L. A. Artifon Hospital Ana Costa. Santos, Brazil. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. São Paulo, Brazil. Profesor
  • Mauricio K. Minata Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. São Paulo, Brazil. Resident physician
  • Marco Antonio B. Cunha Hospital Ana Costa. Santos, Brazil. Assistant physician
  • Jose P. Otoch Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. São Paulo, Brazil. Professor
  • Dayse P. Aparicio Hospital Ana Costa. Santos, Brazil. Assistant physician
  • Carlos K. Furuya Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. São Paulo, Brazil. Assistant physician
  • José L. B. Paione Hospital Ana Costa. Santos, Brazil

DOI:

https://doi.org/10.47892/rgp.2015.354.96

Palabras clave:

Intestinal perforation, Cholangiopancreatography, endoscopic retrograde, Stents, Surgical clips, Surgical procedures, operative

Resumen

Introduction: Duodenal perforations are an uncommon adverse event during ERCP. Patients can develop significant morbidity and mortality. Even though surgery has been used to manage duodenal complications, therapeutic endoscopy has seen significant advances. Objective: To compare endoscopic approach with surgical intervention in patients with duodenal perforations post-ERCP. Material and Methods: prospective randomized study in a tertiary center with 23 patients divided in 2 groups. Within 12 hours after the event, the patients underwent endoscopic or surgical approach. Endoscopic approach included closure of the perforation with endoclips and SEMS. Surgical repair included hepaticojejunostomy, suture of the perforation or duodenal suture. The success was defined as closure of the defect. Secondary outcomes included mortality, adverse events, days of hospitalization and costs. Results: The success was 100% in both groups. There was one death in the endoscopic group secondary to sepsis. There was no statistical difference in mortality or adverse events. We noticed statistical difference in favor of the endoscopic group considering shorter hospitalization (4.1 days versus 15.2 days, with p=0.0123) and lower cost per patient (U$14,700 versus U$19,872, with p=0.0103). Conclusions: Endoscopic approach with SEMS and endoclips is an alternative to surgery in large transmural duodenal perforations post-ERCP.

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Publicado

09.06.2017

Cómo citar

1.
Artifon ELA, Minata MK, Cunha MAB, Otoch JP, Aparicio DP, Furuya CK, Paione JLB. Surgical or endoscopic management for post-ERCP large transmural duodenal perforations: a randomized prospective trial. Rev Gastroenterol Peru [nternet]. 9 de junio de 2017 [citado 20 de julio de 2024];35(4):313-7. isponible en: https://revistagastroperu.com/index.php/rgp/article/view/96

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