Endoscopic-ultrasound versus percutaneous-guided celiac plexus block for chronic pancreatitis pain. A systematic review and meta-analysis

Autores/as

  • Renata Nobre Moura Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Eduardo Guimarães Hourneaux De Moura Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Wanderley Marques Bernardo Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Jose P. Otoch Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Fabio Alberto Castillo Bustamante Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Débora Vieira Albers Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Gustavo Luis Rodela Silva Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Dalton Marques Chaves Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil
  • Everson Luiz de Almeida Artifon Gastrointestinal Endoscopy Unit, University of São Paulo. São Paulo, Brazil

DOI:

https://doi.org/10.47892/rgp.2015.354.99

Palabras clave:

Pancreatitis, chronic, Pain management, Celiac plexus, Endosonography, Meta-analysis

Resumen

Background: Abdominal pain is present in the vast majority of patients with chronic pancreatitis, being frequently debilitating. Celiac plexus block (CPB) is an interventional technique that can be considered to provide a temporary pain relief. Objective: To estimate the effectiveness and safeness of endoscopic-ultrasound (EUS) comparing with percutaneous-guided CBP in patients with pancreatic pain. Methods: A systematic review of English and non-English articles using MEDLINE, EMBASE, LILACS and COCHRANE (via BVS). Study selection and data extraction: Only randomized control trials (RCT) comparing the beneficial and harmful effects of EUS and percutaneous-guided celiac plexus block for managing pancreatic pain were included. Data was extracted and analyzed on variables including pain relief and related procedure complications. Results: Two RCT met the inclusion criteria. Both studies assessed the primary outcome (reduction on pain score) and evaluated adverse effects. The drugs injected were the same; nevertheless percutaneous technique was guided by fluoroscopy in one study and by computer tomography (CT) in other. The results showed that the EUS-CPB group was more effective to reduce pain score after 4 weeks after the procedure, with risk of bias to do this affirmation. No statistical difference in pain relief at 1, 8 and 12 weeks and in complications rates. Conclusions: Based on this systematic review and meta-analysis, no statistically significant difference was noted in pain relief and complications for EUS and percutaneous - CPB.

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Publicado

09.06.2017

Cómo citar

1.
Nobre Moura R, Guimarães Hourneaux De Moura E, Marques Bernardo W, Otoch JP, Castillo Bustamante FA, Vieira Albers D, Rodela Silva GL, Marques Chaves D, de Almeida Artifon EL. Endoscopic-ultrasound versus percutaneous-guided celiac plexus block for chronic pancreatitis pain. A systematic review and meta-analysis. Rev Gastroenterol Peru [nternet]. 9 de junio de 2017 [citado 24 de diciembre de 2024];35(4):333-41. isponible en: https://revistagastroperu.com/index.php/rgp/article/view/99

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