Assessment of gastric-acid suppressants prescribing at an internal medicine service of a tertiary hospital in Latin America: A retrospective record review study

Jean Félix Piñerúa-Gonsálvez; Rosanna del Carmen Zambrano-Infantino; Julio César Albornoz-Sandoval; Pedro Waykin Tong-Morao

doi:10.47892/rgp.2022.424.1418

Authors

Jean Félix Piñerúa-Gonsálvez Gastroenterology and Hepatology Unit, Centro Clínico Andrés Bello. Ciudad Bolívar, Venezuela. Department of Gastroenterology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. http://orcid.org/0000-0002-6033-0242
Rosanna del Carmen Zambrano-Infantino Gastroenterology and Hepatology Unit, Centro Clínico Andrés Bello. Ciudad Bolívar, Venezuela. Department of Nuclear Medicine, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. http://orcid.org/0000-0001-6876-5948
Julio César Albornoz-Sandoval Escuela de Ciencias de la Salud “Francisco Battistini Casalta”, Universidad de Oriente, Ciudad Bolívar, Venezuela. http://orcid.org/0000-0002-4266-4011
Pedro Waykin Tong-Morao Escuela de Ciencias de la Salud “Francisco Battistini Casalta”, Universidad de Oriente, Ciudad Bolívar, Venezuela. http://orcid.org/0000-0002-4137-4821

DOI:

https://doi.org/10.47892/rgp.2022.424.1418

Keywords:

Gastric Acid, Prescription Drug Overuse, Proton Pump Inhibitors, Inappropriate Prescribing

Abstract

Gastric-acid suppressants are one of the most frequently used classes of drugs worldwide. Several studies about their overprescribing have been carried out in recent years. The aim of the study was to assess the appropriateness of these drugs at an internal medicine service of a tertiary hospital in Venezuela. A retrospective record review of patients admitted to the internal medicine service from January 2020 to February 2021 was performed. Data about indications for gastric-acid suppressants, the type used, and their continuation at discharge were collected. The prescribing was grouped into two categories, appropriate or inappropriate, according to current clinical guidelines. Of the 1203 patients who were newly prescribed gastric-acid suppressants in hospital during the study period, 993 (82.5%) had an inappropriate prescription. Prophylaxis of peptic ulcers in low-risk patients was the most frequent no evidence-based indication (20.24%). Seven hundred sixty-two patients were discharged on gastric-acid suppressants. Of these, 74.7% did not have an acceptable indication to continue this treatment on an outpatient basis. Many hospitalized patients in a Venezuelan academi re given gastric acid suppressants not in accordance with the current clinical practice guidelines.

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