Brain gut microbiota axis. Importance in clinical practice

Authors

DOI:

https://doi.org/10.47892/rgp.2022.422.1438

Keywords:

Axis, microbiota-brain-gut, Dysbiosis, Neuropsychiatry, Syndrome, irritable bowel, Probiotics

Abstract

The brain-gut-microbiota axis is a bidirectional complex that connects the central nervous system with the digestive system. Alterations in the composition of the intestinal microbiota have been linked to the presence of digestive and extradigestive diseases such as neuropsychiatric diseases. Dysbiosis predisposes to the appearance of alterations in intestinal permeability, which facilitates the release of neurotransmitters and cytokines that generate favorable conditions for the appearance of a state known as neuroinflammation, which seems to be key in the physiopathogenesis of neuropsychiatric diseases. Based on these data, the modulation of the microbiota through changes in diet, antibiotics and probiotics could be a useful alternative, not only for the treatment of digestive diseases but also extra-digestive disorders such as neuropsychiatric diseases.

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Published

06/30/2022

How to Cite

1.
Bustos-Fernández LM, Hanna-Jairala I. Brain gut microbiota axis. Importance in clinical practice. Rev Gastroenterol Peru [nternet]. 2022 Jun. 30 [cited 2024 Jul. 22];42(2):106-1. vailable from: https://revistagastroperu.com/index.php/rgp/article/view/1438

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Section

ARTÍCULOS DE REVISIÓN