Reduction in Helicobacter pylori infection among patients referred for upper gastrointestinal endoscopy in Santiago, Chile, between 2010-2020
DOI:
https://doi.org/10.47892/rgp.2024.441.1624Keywords:
Bacteria, Endoscopy, gastrointestinal, Gastric CancerAbstract
Latin America presents a high prevalence of Helicobacter pylori (Hp) infection. Between 1996-2003, the prevalence in Santiago, Chile, was 70%; recent studies indicate a decrease in this infection. Updating the frequency of Hp is crucial due to its associated health impact. Objective: Our objective was to describe the trend in Hp infection in patients undergoing ambulatory esophagogastroduodenoscopy (EGD) in a Chilean population. Materials and methods: A retrospective observational study was conducted on patients over 18 years old who attended a first EGD with a rapid urease test between 2010-2020. Time trends were described through time series analysis. A Poisson model was constructed to estimate the risk of infection, adjusted for age and gender. Results: 11,355 patients were included [66.9% females; mean age 52 years; Hp 41.6%]. Male gender presented a higher frequency of Hp infection [RR 1.13; (95% CI: 1.08-1.18)]. Hp frequency infection decreased significantly from 45.1% in 2010 to 29% in 2020, with a 36% lower probability of Hp infection in 2020 compared to 2010 [RR 0.64; (95% CI: 0.55-0.74)]. A progressive decline in Hp infection trend was projected, reaching values close to 25% by year 2025. Conclusion: A significantreduction in Hp infection was observed between 2010-2020. This decrease could be explained by the implementation of public health policies in the last decade associated with socio-sanitary changes.
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Copyright (c) 2024 Felipe Silva, Gonzalo Latorre, Patricio Medel, Miguel Bustamante, Isabella Montero, Camila Robles , Eitan Dukes, Francisca Martinez, María Victoria Binder, Javier Uribe, Diego Reyes , Marcela Bittner , Marisol Sirhan, Manuel Espinoza , Eduardo Fuentes-López, Roberto Candia, Carlos Agüero, José Ignacio Vargas, Alberto Espino, Arnoldo Riquelme
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