Lower gastrointestinal bleeding due to pancreatic cancer: an unusual presentation

Authors

DOI:

https://doi.org/10.47892/rgp.2023.432.1430

Keywords:

Gastrointestinal Hemorrhage, Pancreatic Neoplasms, Abdominal Pain, Colonoscopy

Abstract

Pancreatic cancer is a malignant neoplasm with a poor prognosis. When it manifests clinically with cold jaundice, general repercussion or dyspepsia, it usually corresponds to a locally advanced tumor. Enterorrhagia as a form of presentation of pancreatic cancer is extremely infrequent; it corresponds to a severe form with an ominous prognosis. We present the case of a 61-year-old man who attended emergency service for enterorrhagia associated with organic abdominal pain and general repercussions, to whom a diagnosis of pancreatic tail cancer was diagnosed. Colonoscopy revealed mucosal infiltration with intense edema, erythema, necrosis, and spontaneous bleeding at the level of the splenic flexure of the colon. Histology confirmed colonic infiltration by pancreatic neoplasm. Computed tomography allowed staging in stage IV. Palliative surgical treatment was performed, with a survival of 3 months.

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Author Biographies

Larrosa, Camila, Clínica de Gastroenterología Montevideo, Uruguay

POSTGRADO CLINICA DE GASTROENTEROLOGÍA "PROF. DRA. CAROLINA OLANO"

 

 

Moratorio, Ignacio, Clínica de Gastroenterología Montevideo, Uruguay

GASTROENTEROLOGO

ASISTENTE CLINICA DE GASTROENTEROLOGÍA "PROF. DRA. CAROLINA OLANO"

 

Canavesi, Adrián, Clínica de Gastroenterología Montevideo, Uruguay

GASTROENTEROLOGO

PROF. ADJ. CLINICA DE GASTROENTEROLOGÍA "PROF. DRA. CAROLINA OLANO"

 

 

References

(1) Rawla P, Sunkara T, Gaduputi V. Epidemiology of pancreatic cancer: Global trends, etiology and risk factors. World J Oncol [Internet]. 2019 [cited 2022 Sep 1];10(1):10–27. Available from: http://dx.doi.org/10.14740/wjon1166

(2) Lopez PA. Cáncer de páncreas. Epidemiología de su mal pronóstico. Revista Medica del Uruguay [Internet]. 2017 [cited 2022 Sep 1];33(3):38–57. Available from: http://www.scielo.edu.uy/scielo.php?pid=S1688-03902017000300038&script=sci_abstract&tlng=pt

(3) Pereyra Cosco J, Delgado Galiana JM. Adenocarcinoma de páncreas. Relatos. 1 de enero de 2016; 1-148. DOI: https://doi.org/10.31837/relatos/8

(4) López Serrano A. Factores de riesgo y diagnóstico temprano del cáncer de páncreas. Gastroenterol Hepatol [Internet]. 2010; 33(5): 382–90. DOI: 10.1016/j.gastrohep.2009.10.004

(5) Fernández I, Barrera Z, Riverón E, et al. Tumor de cola de páncreas. Informe de un caso. Rev. Información Científica. 2004; V.

(6) Khosravi Shahi P, Díaz Muñoz de la Espada VM. Adenocarcinoma de páncreas: actualizaciones terapéuticas. An Med Interna. 2005; 22(8): 390–4.

(7) Beetz O, Sarisin A, Kaltenborn A, et al. Multivisceral resection for adenocarcinoma of the pancreatic body and tail-a retrospective single-center analysis. World J Surg Oncol. 2020; 18(1): 218. DOI: 10.1186/s12957-020-01973-x

(8) Wang YU, Yuan C, Liu X. Characteristics of gastrointestinal hemorrhage associated with pancreatic cancer: A retrospective review of 246 cases. Mol Clin Oncol. 2015; 3(4): 902–8. DOI: 10.3892/mco.2015.563

(9) Harada S, Lida T, Asai S, et al. Successful en bloc resection of locally advanced pancreatic tail cancer with colonic perforation following neoadjuvant chemotherapy: A case report. Am J Case Rep. 2021; 22: e933226. DOI: 10.12659/AJCR.933226

(10) Aguilera Munoz L, de Mestier L, Lamallem H, et al. Gastrointestinal bleeding in patients with pancreatic cancer: Causes and haemostatic treatments. United European Gastroenterol J. 2020; 8(9): 1106–14. DOI: 10.1177/2050640620939788

(11) Cárdenas J, Agamez C, Parra S. Obstrucción intestinal maligna. Revisión de tema. Rev colomb cancerol. 2013; 17(2): 77–85.

(12) Marco PC, Rosario MD, Rodenas JP, et al. TCMD en la estadificación local del adenocarcinoma de páncreas: comparación con ecoendoscopia. Espacio-seram.com.

(13) Montejo Gañán I, Ángel Ríos LF, Sarría Octavio de Toledo L,et al. Estadificación mediante tomografía computarizada del carcinoma de páncreas. Radiol. 2018; 60(1): 10–23. DOI: 10.1016/j.rx.2017.08.004

(14) Kutluturk K, Alam AH, Kayaalp C, et al. En masse resection of pancreas, spleen, celiac axis, stomach, kidney, adrenal, and colon for invasive pancreatic corpus and tail tumor. Case Rep Surg. 2013; 2013: 376035. DOI: 10.1155/2013/376035

(15) Ohtsubo K, Watanabe H, Mouri H, Yamashita K, Yasumoto K, Yano S. Endoscopic findings of upper gastrointestinal lesions in patients with pancreatic cancer . JOP 2012; 13(4):420–6. DOI: 10.6092/1590-8577/749

Published

06/30/2023

How to Cite

1.
Larrosa C, Moratorio I, Canavesi A. Lower gastrointestinal bleeding due to pancreatic cancer: an unusual presentation. Rev Gastroenterol Peru [nternet]. 2023 Jun. 30 [cited 2024 Dec. 3];43(2):e1430. vailable from: https://revistagastroperu.com/index.php/rgp/article/view/1430

Issue

Section

REPORTES DE CASOS